The injuries happened in Lockett, Texas, according to a local journalist. Photos posted to social media showed power transmission lines completely bent on their sides, trees ripped up and homes damaged.

A sheriff's department employee in Wilbarger County, Texas, where Lockett is located, told weather.com in a phone call Wednesday night that there was "extensive structural damage" in the town.

Lockett is on the Oklahoma border about 50 miles northwest of Wichita Falls.

(MORE: Where Severe Thunderstorms Will Persist Into the Weekend)

Further north in Oklahoma, cell phone alerts went out to residents in Seminole at about 6:30 p.m. local time Wednesday night.

Then came the tornado sirens.

When it was all over, buildings were ripped apart, homes missing roofs and debris strewn through streets and neighborhoods.

“The devastation is amazing, what’s happened to the buildings," Audrey Reed, who lives in the town of about 7,000 people, told weather.com in an interview Thursday morning. "Some buildings are completely gone, houses are gone."

Reed hunkered down in a closet with her dogs as the storm passed. Her home escaped major damage besides a lot of downed trees to clean up, but others nearby weren't so lucky.

“The neighbor behind me, her roof came completely off and everything basically in her house is in my backyard," Reed said. "I have a sturdy little house, thank goodness.

(MORE: Storm Chasing Tour Van Hit by Reported Tornado in Texas)

Half a mile away in downtown Seminole, windows were blown out of buildings and brick walls collapsed.

"Telephone poles (are) down everywhere, laying across the road," Reed said of the downtown area. "I’ve seen approximately 100 power trucks getting ready to go restore power since nobody in town has power."

Police came through Wednesday night to check on everyone. There were no reports of major injuries or deaths.

"We’re all safe, and that’s the main thing. We're all safe," Reed said.

The system was also responsible for spawning several other damaging tornadoes and flooding that prompted evacuations.

In Arkansasa Thursday morning, officials were evacuating residents near Fayetteville as homes and vehicles were flooded. The National Weather Service issued a flash flood warning for the city of 85,000 as floodwaters rose and heavy rain refused to relent.

State troopers were among the many agencies assisting in the response to the tornado damage in Seminole.

"They’re going from place to place making sure that no one else is in need of help," Trooper Eric Foster told KWTV Wednesday night. "It's not one big metropolis there. There are homes across the countryside."

First responders and residents in the area had to take cover again as more storms moved through after the initial tornado.

Video and photos shared on social media and aired by local TV stations showed menacing clouds, blown-out windows and other damage in Seminole.

A broad circulation moved through the region along a warm front and produced multiple tornadoes.

Seminole Public Schools were closed Thursday, according to KWTV. The Academy of Seminole, a public charter school, took a direct hit from the tornado, according to a Facebook post from the school.

"We will be (assessing) the damage over the next few days," the post read. "Please do not come to the school: it is extremely dangerous. Everyone who was at the school is safe."

(MORE: Drone View of Damage in Seminole, Oklahoma)

About 14,000 power outages were being reported in Oklahoma as of about 9:45 p.m. CT Wednesday, according to PowerOutage.us. Most were in Seminole County and neighboring Hughes County. That number had dropped to about 10,000 by Thursday morning.

The town of Seminole has a population of about 7,200, while about 23,500 people live in the county as a whole.

Hail also rained down across the region, with some larger than 2 inches reported Wednesday afternoon in southwest Oklahoma. Hail also fell in parts of the Texas Panhandle and Kansas.

A tornado was reported shortly before 6 p.m. CT in Dickens County in the Texas Panhandle, about 50 miles east of Lubbock. That tornado tracked east to south of Paducah, Texas.

And a tornado near Crowell in Foard County, Texas, was seen on video crossing a highway.

Earlier on Wednesday in Kansas, at least three people were injured by separate lightning strikes in the Wichita area, local media outlets reported. One was an airman on the flight line at McConnell Air Force Base who was conscious but was transported to a local hospital, according to a news release.

Severe weather is expected to continue into the weekend for parts of the Plains, Midwest and South.

Anyone in the potential path of storms should have a severe weather plan, including where to take shelter, and multiple ways of receiving National Weather Service watches and warnings via smartphone wireless emergency alerts, The Weather Channel app and NOAA weather radio.

The Weather Company’s primary journalistic mission is to report on breaking weather news, the environment and the importance of science to our lives. This story does not necessarily represent the position of our parent company, IBM.